The INSB200™ Difference
Journey of a PNB Injection
INSB200™ is designed to deliver sustained analgesia (or pain relief). Our proprietary depot technology elutes ropivacaine from the injection site to adjacent peripheral nerves, providing several days of extended pain relief.
01
Injection

The INSB200™ liquid PNB formulation is injected adjacent to the target peripheral nerve bundle.
02
Initial Release

Following injection, ropivacaine is released at a rate sufficient to produce a nerve block and reaches its maximum blood concentration.
03
Sustained Pain Relief

Ropivacaine is gradually released from the emulsion at a clinically significant level to manage pain and eliminate the need for opioid rescue medications.
04
Gradual Clearance


As the product is used up, ropivacaine concentrations gradually decline and the drug is eliminated from the patient.
05
Natural Elimination
The INSB200™ sustained-release emulsion carrier is naturally eliminated from the injection site and the body.